几块钱一管的维A酸乳膏，是“护肤圣品”还是致癌毒物？

[2] Ramchatesingh B, Martínez Villarreal A, et al. The Use of Retinoids for the Prevention and Treatment of Skin Cancers: An Updated Review. Int J Mol Sci. 2022; 23(20)： 12622.

[3] Motamedi M, Chehade A, Sanghera R, et al. A Clinician's Guide to Topical Retinoids. J Cutan Med Surg. 2022; 26(1)： 71-78.

[4] Goldfarb, Michael T. et al. Retinoids in Dermatology. Mayo Clin Proc. 1987; 62(12)： 1161 – 1164.

[5] Retinoid or retinol? https://www.aad.org/public/everyday-care/skin-care-secrets/anti-aging/retinoid-retinol

[6] Narsa AC, Suhandi C, Afidika J, et al. A Comprehensive Review of the Strategies to Reduce Retinoid-Induced Skin Irritation in Topical Formulation. Dermatol Res Pract. 2024; 2024: 5551774.

[7] What is retinol burn and how to prevent it? https://www.healthline.com/health/retinol-burn

[8] Understanding retinoids & retinol skin care. https://ensoulclinic.com/understanding-retinoids-retinol-skin-care/

[9] Bushue N, Wan YJ. Retinoid pathway and cancer therapeutics. Adv Drug Deliv Rev. 2010; 62(13)： 1285-1298.

[10] Uptodate. 维A酸. https://www.uptodate.com/

[11] 西安交通大学第二医院皮肤科.维A酸类药物的分类及在皮肤科中的应用.2006中国中西医结合皮肤性病学术会议论文汇编， 2006. [2006-09-01]

[12]维基百科. 维A酸. https://zh.wikipedia.org/

Kligman LH, Kligman AM. Lack of enhancement of experimental photocarcinogenesis by topical retinoic acid. Arch Dermatol Res. 1981; 270(4)： 453-462.

Rosso JD, Harper J, Pillai R, et al. Tretinoin photostability: comparison of micronized tretinoin gel 0.05% and tretinoin gel 0.025% following exposure to fluorescent and solar light. J Clin Aesthet Dermatol. 2013; 6(2)： 25-28.

策划制作

作者丨唐教清 皮肤科主治医师 中国科普作家协会会员

审核丨徐敏 天津医科大学代谢病医院(天津医科大学朱宪彝纪念医院)皮肤科副主任医师 天津市医学会皮肤性病学分会委员

策划丨杨雅萍